11 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lexington | 1 | 26,204 | 23,653 | 1.65% | 2,073 | 13 | Town |
| West Columbia | 2 | 18,869 | 17,516 | 1.21% | 2,013 | 9 | City |
| Cayce | 3 | 13,589 | 13,756 | -0.21% | 805 | 17 | City |
| Springdale | 4 | 2,764 | 2,740 | 0.14% | 1,022 | 3 | Town |
| South Congaree | 5 | 2,396 | 2,384 | 0.08% | 729 | 3 | Town |
| Chapin | 6 | 1,993 | 1,816 | 1.53% | 893 | 2 | Town |
| Gaston | 7 | 1,658 | 1,606 | 0.55% | 312 | 5 | Town |
| Swansea | 8 | 793 | 727 | 1.41% | 380 | 2 | Town |
| Gilbert | 9 | 638 | 577 | 1.59% | 235 | 3 | Town |
| Pelion | 10 | 620 | 628 | -0.16% | 144 | 4 | Town |
| Summit | 11 | 478 | 423 | 1.92% | 321 | 1 | Town |
Lexington is the largest city in Lexington County, with a population of 26,204.
Summit is the smallest city in Lexington County, with a population of 478.
There are 11 cities in Lexington County, South Carolina.