| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lexington | 1 | 26,155 | 23,720 | 1.66% | 2,069 | 13 | Town |
| West Columbia | 2 | 18,726 | 17,489 | 1.28% | 1,998 | 9 | City |
| Cayce | 3 | 13,664 | 13,778 | -0.12% | 809 | 17 | City |
| Springdale | 4 | 2,883 | 2,738 | 0.21% | 1,066 | 3 | Town |
| South Congaree | 5 | 2,424 | 2,422 | 0% | 737 | 3 | Town |
| Chapin | 6 | 1,974 | 1,808 | 1.49% | 884 | 2 | Town |
| Gaston | 7 | 1,658 | 1,616 | 0.42% | 312 | 5 | Town |
| Swansea | 8 | 788 | 725 | 1.42% | 378 | 2 | Town |
| Gilbert | 9 | 649 | 582 | 1.72% | 239 | 3 | Town |
| Pelion | 10 | 624 | 632 | -0.16% | 145 | 4 | Town |
| Summit | 11 | 472 | 422 | 1.72% | 317 | 1 | Town |
Lexington is the largest city in Lexington County, with a population of 26,155.
Summit is the smallest city in Lexington County, with a population of 472.
There are 11 cities in Lexington County, South Carolina.