| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Jackson | 1 | 4,388 | 4,742 | -1.44% | 281 | 16 | City |
| Thomasville | 2 | 3,508 | 3,705 | -1.04% | 312 | 11 | City |
| Grove Hill | 3 | 1,686 | 1,811 | -1.29% | 222 | 8 | Town |
| Coffeeville | 4 | 247 | 258 | -0.8% | 55 | 5 | Town |
| Fulton | 5 | 211 | 223 | -0.94% | 86 | 2 | Town |
Jackson is the largest city in Clarke County, with a population of 4,388.
Fulton is the smallest city in Clarke County, with a population of 211.
There are 5 cities in Clarke County, Alabama.