8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Dumas | 1 | 3,513 | 3,968 | -2.52% | 1,209 | 3 | City |
| McGehee | 2 | 3,417 | 3,851 | -2.48% | 509 | 7 | City |
| Arkansas City | 3 | 337 | 377 | -2.32% | 685 | 0 | City |
| Mitchellville | 4 | 252 | 284 | -2.7% | 2,100 | 0 | City |
| Watson | 5 | 160 | 183 | -3.03% | 800 | 0 | City |
| Tillar | 6 | 156 | 165 | -1.27% | 199 | 1 | City |
| Reed | 7 | 112 | 126 | -2.61% | 552 | 0 | Town |
| Symonds | 8 | 34 | 17 | 6.25% | 472 | 0 | CDP |
Dumas is the largest city in Desha County, with a population of 3,513.
Symonds is the smallest city in Desha County, with a population of 34.
There are 8 cities in Desha County, Arkansas.