7 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Dumas | 1 | 3,422 | 3,968 | -2.59% | 1,178 | 3 | City |
| McGehee | 2 | 3,330 | 3,851 | -2.55% | 496 | 7 | City |
| Arkansas City | 3 | 329 | 377 | -2.37% | 669 | 0 | City |
| Mitchellville | 4 | 246 | 284 | -2.38% | 2,050 | 0 | City |
| Watson | 5 | 156 | 183 | -2.5% | 780 | 0 | City |
| Tillar | 6 | 154 | 165 | -1.28% | 196 | 1 | City |
| Reed | 7 | 109 | 126 | -2.68% | 537 | 0 | Town |
Dumas is the largest city in Desha County, with a population of 3,422.
Reed is the smallest city in Desha County, with a population of 109.
There are 7 cities in Desha County, Arkansas.