| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Dumas | 1 | 3,381 | 3,971 | -2.73% | 1,163 | 3 | City |
| McGehee | 2 | 3,302 | 3,845 | -2.57% | 492 | 7 | City |
| Arkansas City | 3 | 328 | 378 | -2.38% | 667 | 0 | City |
| Mitchellville | 4 | 252 | 288 | -2.33% | 2,100 | 0 | City |
| Tillar | 5 | 158 | 169 | -1.25% | 201 | 1 | City |
| Watson | 6 | 155 | 182 | -3.13% | 775 | 0 | City |
| Reed | 7 | 110 | 126 | -2.65% | 542 | 0 | Town |
Dumas is the largest city in Desha County, with a population of 3,381.
Reed is the smallest city in Desha County, with a population of 110.
There are 7 cities in Desha County, Arkansas.