| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Brinkley | 1 | 2,424 | 2,694 | -1.78% | 426 | 6 | City |
| Clarendon | 2 | 1,371 | 1,513 | -1.65% | 784 | 2 | City |
| Holly Grove | 3 | 425 | 471 | -1.85% | 423 | 1 | City |
| Roe | 4 | 73 | 79 | -1.35% | 408 | 0 | Town |
| Fargo | 5 | 57 | 61 | -1.72% | 125 | 0 | Town |
Brinkley is the largest city in Monroe County, with a population of 2,424.
Fargo is the smallest city in Monroe County, with a population of 57.
There are 5 cities in Monroe County, Arkansas.