| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Piggott | 1 | 3,481 | 3,628 | -0.77% | 645 | 5 | City |
| Corning | 2 | 3,030 | 3,220 | -1.14% | 825 | 4 | City |
| Rector | 3 | 1,773 | 1,845 | -0.89% | 1,301 | 1 | City |
| St. Francis | 4 | 209 | 217 | -0.95% | 589 | 0 | City |
| Pollard | 5 | 184 | 194 | -1.08% | 620 | 0 | City |
| Greenway | 6 | 169 | 174 | -1.17% | 650 | 0 | City |
| Knobel | 7 | 142 | 147 | -0.7% | 337 | 0 | City |
| McDougal | 8 | 125 | 132 | -1.57% | 337 | 0 | Town |
| Peach Orchard | 9 | 102 | 105 | -0.97% | 99 | 1 | City |
| Success | 10 | 95 | 98 | -1.04% | 426 | 0 | Town |
| Nimmons | 11 | 63 | 67 | -1.56% | 252 | 0 | Town |
| Datto | 12 | 61 | 65 | -1.61% | 98 | 1 | Town |
Piggott is the largest city in Clay County, with a population of 3,481.
Datto is the smallest city in Clay County, with a population of 61.
There are 12 cities in Clay County, Arkansas.