| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Pine Bluff | 1 | 37,657 | 40,977 | -1.46% | 852 | 44 | City |
| White Hall | 2 | 5,508 | 5,631 | -0.43% | 780 | 7 | City |
| Redfield | 3 | 1,490 | 1,499 | -0.13% | 482 | 3 | City |
| Altheimer | 4 | 630 | 696 | -1.87% | 307 | 2 | City |
| Humphrey | 5 | 424 | 462 | -1.4% | 325 | 1 | City |
| Wabbaseka | 6 | 165 | 182 | -1.79% | 480 | 0 | Town |
| Allport | 7 | 89 | 90 | -1.11% | 428 | 0 | Town |
| Sherrill | 8 | 50 | 56 | -1.96% | 379 | 0 | Town |
Pine Bluff is the largest city in Jefferson County, with a population of 37,657.
Sherrill is the smallest city in Jefferson County, with a population of 50.
There are 8 cities in Jefferson County, Arkansas.