9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Pine Bluff | 1 | 37,886 | 40,978 | -1.6% | 857 | 44.18 | City |
| White Hall | 2 | 5,357 | 5,556 | -0.74% | 758 | 7.06 | City |
| Redfield | 3 | 1,484 | 1,499 | -0.2% | 480 | 3.09 | City |
| Altheimer | 4 | 630 | 697 | -2.02% | 307 | 2.05 | City |
| Humphrey | 5 | 433 | 462 | -1.37% | 332 | 1.31 | City |
| Wabbaseka | 6 | 168 | 183 | -1.75% | 488 | 0.34 | Town |
| Tucker | 7 | 124 | 67 | 6.9% | 151 | 0.82 | CDP |
| Allport | 8 | 90 | 89 | 0% | 433 | 0.21 | Town |
| Sherrill | 9 | 49 | 56 | -2% | 371 | 0.13 | Town |
Pine Bluff is the largest city in Jefferson County, with a population of 37,886.
Sherrill is the smallest city in Jefferson County.
There are 9 cities in Jefferson County, Arkansas.