5 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Brinkley | 1 | 2,500 | 2,690 | -1.5% | 440 | 6 | City |
| Clarendon | 2 | 1,419 | 1,519 | -1.39% | 811 | 2 | City |
| Holly Grove | 3 | 429 | 464 | -1.61% | 427 | 1 | City |
| Roe | 4 | 67 | 72 | -1.47% | 374 | 0 | Town |
| Fargo | 5 | 55 | 58 | -1.79% | 120 | 0 | Town |
Brinkley is the largest city in Monroe County, with a population of 2,500.
Fargo is the smallest city in Monroe County, with a population of 55.
There are 5 cities in Monroe County, Arkansas.