5 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Des Arc | 1 | 1,813 | 1,897 | -0.77% | 863 | 2 | City |
| Hazen | 2 | 1,345 | 1,473 | -1.54% | 382 | 4 | City |
| De Valls Bluff | 3 | 482 | 520 | -1.23% | 441 | 1 | City |
| Fredonia (Biscoe) | 4 | 288 | 306 | -1.03% | 302 | 1 | Town |
| Ulm | 5 | 180 | 174 | 0.56% | 690 | 0 | Town |
Des Arc is the largest city in Prairie County, with a population of 1,813.
Ulm is the smallest city in Prairie County, with a population of 180.
There are 5 cities in Prairie County, Arkansas.