5 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Des Arc | 1 | 1,806 | 1,903 | -1.04% | 859 | 2.10 | City |
| Hazen | 2 | 1,391 | 1,471 | -1.14% | 395 | 3.52 | City |
| De Valls Bluff | 3 | 490 | 519 | -1.21% | 449 | 1.09 | City |
| Fredonia (Biscoe) | 4 | 293 | 303 | -0.68% | 307 | 0.95 | Town |
| Ulm | 5 | 180 | 174 | 0.56% | 690 | 0.26 | Town |
Des Arc is the largest city in Prairie County, with a population of 1,806.
Ulm is the smallest city in Prairie County.
There are 5 cities in Prairie County, Arkansas.