14 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Clermont | 1 | 52,728 | 43,340 | 3.69% | 2,749 | 19 | City |
| Leesburg | 2 | 40,487 | 27,127 | 7.07% | 933 | 43 | City |
| Groveland | 3 | 26,030 | 18,887 | 5.8% | 1,171 | 22 | City |
| Eustis | 4 | 25,525 | 23,233 | 1.83% | 2,211 | 12 | City |
| Tavares | 5 | 22,754 | 19,019 | 3.39% | 1,844 | 12 | City |
| Minneola | 6 | 21,043 | 14,201 | 6.95% | 1,890 | 11 | City |
| Mount Dora | 7 | 18,725 | 16,405 | 2.54% | 2,090 | 9 | City |
| Lady Lake | 8 | 17,603 | 16,028 | 1.82% | 1,885 | 9 | Town |
| Mascotte | 9 | 9,753 | 6,737 | 6.59% | 730 | 13 | City |
| Fruitland Park | 10 | 9,095 | 8,430 | 1.48% | 1,280 | 7 | City |
| Umatilla | 11 | 4,033 | 3,747 | 1.43% | 1,105 | 4 | City |
| Astatula | 12 | 2,357 | 1,899 | 4.02% | 752 | 3 | Town |
| Montverde | 13 | 1,848 | 1,663 | 2.04% | 998 | 2 | Town |
| Howey-in-the-Hills | 14 | 1,705 | 1,643 | 0.71% | 542 | 3 | Town |
Clermont is the largest city in Lake County, with a population of 52,728.
Howey-in-the-Hills is the smallest city in Lake County, with a population of 1,705.
There are 14 cities in Lake County, Florida.