| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Clermont | 1 | 54,663 | 43,297 | 3.5% | 2,850 | 19 | City |
| Leesburg | 2 | 41,549 | 27,147 | 6.8% | 958 | 43 | City |
| Groveland | 3 | 26,952 | 18,873 | 5.59% | 1,212 | 22 | City |
| Eustis | 4 | 25,939 | 23,231 | 1.79% | 2,247 | 12 | City |
| Tavares | 5 | 23,229 | 19,014 | 3.29% | 1,882 | 12 | City |
| Minneola | 6 | 22,420 | 14,203 | 6.44% | 2,013 | 11 | City |
| Mount Dora | 7 | 19,253 | 16,360 | 2.46% | 2,149 | 9 | City |
| Lady Lake | 8 | 17,811 | 16,052 | 1.8% | 1,908 | 9 | Town |
| Mascotte | 9 | 10,750 | 6,735 | 5.91% | 805 | 13 | City |
| Fruitland Park | 10 | 9,681 | 8,436 | 1.45% | 1,363 | 7 | City |
| Umatilla | 11 | 4,256 | 3,749 | 1.36% | 1,166 | 4 | City |
| Astatula | 12 | 2,404 | 1,902 | 3.89% | 767 | 3 | Town |
| Montverde | 13 | 1,872 | 1,662 | 1.96% | 1,011 | 2 | Town |
| Howey-in-the-Hills | 14 | 1,870 | 1,645 | 0.7% | 595 | 3 | Town |
Clermont is the largest city in Lake County, with a population of 54,663.
Howey-in-the-Hills is the smallest city in Lake County, with a population of 1,870.
There are 14 cities in Lake County, Florida.