10 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Muscatine | 1 | 23,183 | 23,757 | -0.49% | 1,274 | 18 | City |
| West Liberty | 2 | 3,692 | 3,850 | -0.86% | 2,089 | 2 | City |
| Wilton | 3 | 2,913 | 2,917 | -0.03% | 1,418 | 2 | City |
| Fruitland | 4 | 920 | 959 | -0.86% | 512 | 2 | City |
| Conesville | 5 | 349 | 352 | -0.29% | 972 | 0 | City |
| Nichols | 6 | 314 | 328 | -0.95% | 1,377 | 0 | City |
| Atalissa | 7 | 284 | 296 | -1.05% | 2,043 | 0 | City |
| Stockton | 8 | 169 | 176 | -1.17% | 1,550 | 0 | City |
| Maysville | 9 | 155 | 155 | 0% | 566 | 0 | City |
| Welton | 10 | 123 | 128 | -0.81% | 468 | 0 | City |
Muscatine is the largest city in Muscatine County, with a population of 23,183.
Welton is the smallest city in Muscatine County, with a population of 123.
There are 10 cities in Muscatine County, Iowa.