13 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Muscatine | 1 | 23,071 | 23,745 | -0.58% | 1,268 | 18.20 | City |
| West Liberty | 2 | 3,646 | 3,851 | -1.11% | 2,063 | 1.77 | City |
| Wilton | 3 | 2,937 | 2,919 | 0.14% | 1,429 | 2.06 | City |
| Fruitland | 4 | 910 | 959 | -1.09% | 506 | 1.80 | City |
| Conesville | 5 | 343 | 350 | -0.29% | 955 | 0.36 | City |
| Moscow | 6 | 342 | 235 | 6.88% | 287 | 1.19 | CDP |
| Nichols | 7 | 321 | 338 | -0.93% | 1,408 | 0.23 | City |
| Atalissa | 8 | 281 | 296 | -1.06% | 2,022 | 0.14 | City |
| Montpelier | 9 | 215 | 157 | 6.97% | 439 | 0.49 | CDP |
| Stockton | 10 | 168 | 177 | -1.18% | 1,541 | 0.11 | City |
| Maysville | 11 | 152 | 157 | -0.65% | 555 | 0.27 | City |
| Welton | 12 | 126 | 128 | 0% | 455 | 0.28 | City |
| Plainview | 13 | 13 | 11 | 8.33% | 24 | 0.55 | CDP |
Muscatine is the largest city in Muscatine County, with a population of 23,071.
Plainview is the smallest city in Muscatine County.
There are 13 cities in Muscatine County, Iowa.