8 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Corydon | 1 | 1,583 | 1,523 | 0.64% | 1,158 | 1 | City |
| Seymour | 2 | 651 | 636 | 0.46% | 272 | 2 | City |
| Humeston | 3 | 475 | 465 | 0.42% | 761 | 1 | City |
| Allerton | 4 | 434 | 428 | 0.23% | 366 | 1 | City |
| Lineville | 5 | 195 | 192 | 0.52% | 216 | 1 | City |
| Promise City | 6 | 92 | 89 | 1.1% | 500 | 0 | City |
| Clio | 7 | 67 | 66 | 0% | 90 | 1 | City |
| Millerton | 8 | 37 | 36 | 0% | 127 | 0 | City |
Corydon is the largest city in Wayne County, with a population of 1,583.
Millerton is the smallest city in Wayne County, with a population of 37.
There are 8 cities in Wayne County, Iowa.