5 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Henderson | 1 | 27,653 | 28,136 | -0.35% | 1,636 | 17 | City |
| Corydon | 2 | 720 | 729 | -0.28% | 1,326 | 1 | City |
| Robards | 3 | 444 | 448 | -0.22% | 147 | 3 | City |
| Anthoston | 4 | 376 | 284 | 7.12% | 583 | 1 | CDP |
| Spottsville | 5 | 161 | 355 | -6.4% | 342 | 0 | CDP |
Henderson is the largest city in Henderson County, with a population of 27,653.
Spottsville is the smallest city in Henderson County, with a population of 161.
There are 5 cities in Henderson County, Kentucky.