7 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Jenkins | 1 | 1,721 | 1,895 | -1.99% | 195 | 8.85 | City |
| Whitesburg | 2 | 1,586 | 1,765 | -2.22% | 506 | 3.13 | City |
| Millstone | 3 | 814 | 473 | 5.99% | 3,804 | 0.21 | CDP |
| McRoberts | 4 | 711 | 790 | -0.7% | 127 | 5.60 | CDP |
| Mayking | 5 | 537 | 513 | 0.56% | 349 | 1.54 | CDP |
| Fleming-Neon | 6 | 506 | 543 | -1.36% | 313 | 1.61 | City |
| Payne Gap | 7 | 205 | 588 | -4.21% | 89 | 2.30 | CDP |
Jenkins is the largest city in Letcher County, with a population of 1,721.
Payne Gap is the smallest city in Letcher County.
There are 7 cities in Letcher County, Kentucky.