6 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Central City | 1 | 5,706 | 5,819 | -0.33% | 1,090 | 5 | City |
| Greenville | 2 | 4,290 | 4,479 | -0.72% | 835 | 5 | City |
| Powderly | 3 | 787 | 786 | 0% | 504 | 2 | City |
| Drakesboro | 4 | 470 | 478 | -0.21% | 851 | 1 | City |
| Bremen | 5 | 170 | 173 | 0% | 821 | 0 | City |
| South Carrollton | 6 | 137 | 139 | 0% | 542 | 0 | City |
Central City is the largest city in Muhlenberg County, with a population of 5,706.
South Carrollton is the smallest city in Muhlenberg County, with a population of 137.
There are 6 cities in Muhlenberg County, Kentucky.