| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Central City | 1 | 5,774 | 5,818 | -0.33% | 1,103 | 5 | City |
| Greenville | 2 | 4,322 | 4,482 | -0.64% | 842 | 5 | City |
| Powderly | 3 | 788 | 776 | 0.13% | 504 | 2 | City |
| Drakesboro | 4 | 465 | 474 | -0.43% | 842 | 1 | City |
| Bremen | 5 | 172 | 175 | -0.58% | 831 | 0 | City |
| South Carrollton | 6 | 142 | 144 | -0.7% | 561 | 0 | City |
Central City is the largest city in Muhlenberg County, with a population of 5,774.
South Carrollton is the smallest city in Muhlenberg County, with a population of 142.
There are 6 cities in Muhlenberg County, Kentucky.