| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Carlisle | 1 | 2,114 | 2,103 | -0.38% | 1,587 | 1 | City |
Carlisle is the largest city in Nicholas County, with a population of 2,114.
Carlisle is the smallest city in Nicholas County, with a population of 2,114.
There is 1 city in Nicholas County, Kentucky.