18 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Waldorf | 1 | 84,408 | 77,711 | 1.33% | 2,329 | 36.24 | CDP |
| Bensville | 2 | 17,752 | 13,658 | 7.14% | 1,050 | 16.90 | CDP |
| Rosaryville | 3 | 12,358 | 11,344 | 0.9% | 1,346 | 9.18 | CDP |
| La Plata | 4 | 11,330 | 10,199 | 2.04% | 1,522 | 7.45 | Town |
| Bryans Road | 5 | 8,929 | 8,198 | 1.27% | 580 | 15.38 | CDP |
| Indian Head | 6 | 4,357 | 3,889 | 2.21% | 3,542 | 1.23 | Town |
| Golden Beach | 7 | 3,967 | 3,620 | 0.28% | 1,046 | 3.79 | CDP |
| Croom | 8 | 2,895 | 2,353 | 0.63% | 85 | 34.19 | CDP |
| Hughesville | 9 | 2,324 | 2,525 | 0.35% | 208 | 11.15 | CDP |
| Baden | 10 | 1,846 | 1,574 | -0.97% | 67 | 27.60 | CDP |
| Cobb Island | 11 | 1,331 | 1,119 | 0.83% | 2,126 | 0.63 | CDP |
| Potomac Heights | 12 | 1,178 | 1,247 | 0.34% | 1,098 | 1.07 | CDP |
| Cedarville | 13 | 854 | 577 | 1.07% | 64 | 13.28 | CDP |
| Pomfret | 14 | 823 | 396 | 2.49% | 300 | 2.74 | CDP |
| Bryantown | 15 | 611 | 464 | -0.49% | 147 | 4.14 | CDP |
| Benedict | 16 | 118 | 181 | -7.81% | 506 | 0.23 | CDP |
| Rock Point | 17 | 78 | 63 | -2.5% | 124 | 0.63 | CDP |
| Port Tobacco Village | 18 | 25 | 25 | 0% | 136 | 0.18 | Town |
Waldorf is the largest city in Charles County, with a population of 84,408.
Port Tobacco Village is the smallest city in Charles County, with a population of 25.
There are 18 cities in Charles County, Maryland.