4 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Greenwood | 1 | 13,122 | 14,637 | -1.88% | 1,064 | 12 | City |
| Itta Bena | 2 | 1,439 | 1,669 | -2.57% | 1,020 | 1 | City |
| Schlater | 3 | 213 | 234 | -1.39% | 185 | 1 | Town |
| Morgan City | 4 | 184 | 207 | -2.13% | 313 | 1 | Town |
Greenwood is the largest city in Leflore County, with a population of 13,122.
Morgan City is the smallest city in Leflore County, with a population of 184.
There are 4 cities in Leflore County, Mississippi.