4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Booneville | 1 | 9,415 | 9,174 | 0.51% | 366 | 26 | City |
| Jumpertown | 2 | 430 | 423 | 0.23% | 240 | 2 | Town |
| Marietta | 3 | 193 | 193 | 0% | 108 | 2 | Town |
| Paden | 4 | 104 | 106 | -0.95% | 116 | 1 | Village |
Booneville is the largest city in Prentiss County, with a population of 9,415.
Paden is the smallest city in Prentiss County, with a population of 104.
There are 4 cities in Prentiss County, Mississippi.