There are 14 cities in Perry County, Missouri.
Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Population | 2020 Population | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Perryville | 1 | 8,488 | 8,558 | -0.21% | 1,040 | 8.2 | City |
| Shakertowne | 2 | 527 | 545 | 7.55% | 399 | 1.3 | CDP |
| Brewer | 3 | 494 | 466 | 1.65% | 211 | 2.3 | CDP |
| Altenburg | 4 | 338 | 344 | -0.59% | 322 | 1.1 | City |
| St. Mary | 5 | 307 | 306 | 0% | 513 | 0.6 | City |
| Ozora | 6 | 290 | 109 | 2.47% | 47 | 6.1 | CDP |
| Frohna | 7 | 243 | 245 | -0.41% | 269 | 0.9 | City |
| Sedgewickville | 8 | 187 | 189 | -0.53% | 292 | 0.6 | Village |
| Longtown | 9 | 90 | 92 | -1.1% | 720 | 0.1 | Town |
| Old Appleton | 10 | 71 | 71 | 0% | 587 | 0.1 | Town |
| Lithium | 11 | 55 | 88 | 7.84% | 71 | 0.8 | CDP |
| Biehle | 12 | 43 | 28 | 7.5% | 194 | 0.2 | CDP |
| New Wells | 13 | 38 | 41 | 5.56% | 65 | 0.6 | CDP |
| Kaskaskia | 14 | 23 | 23 | 0% | 217 | 0.1 | Village |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Perryville is the largest city in Perry County.
Kaskaskia is the smallest city in Perry County.
There are 14 cities in Perry County, Missouri.