9 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Moberly | 1 | 13,108 | 13,577 | -0.71% | 995 | 13.18 | City |
| Huntsville | 2 | 1,347 | 1,372 | -0.37% | 581 | 2.32 | City |
| Brewer | 3 | 503 | 466 | 1.82% | 215 | 2.34 | CDP |
| Higbee | 4 | 441 | 448 | -0.23% | 1,114 | 0.40 | City |
| Clark | 5 | 246 | 250 | -0.4% | 411 | 0.60 | City |
| Cairo | 6 | 202 | 204 | 0% | 673 | 0.30 | Village |
| Renick | 7 | 149 | 151 | 0% | 413 | 0.36 | Village |
| Jacksonville | 8 | 120 | 122 | 0% | 1,091 | 0.11 | Village |
| Clifton Hill | 9 | 85 | 87 | 0% | 486 | 0.17 | City |
Moberly is the largest city in Randolph County, with a population of 13,108.
Clifton Hill is the smallest city in Randolph County.
There are 9 cities in Randolph County, Missouri.