| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Moberly | 1 | 13,731 | 13,587 | 0.09% | 1,042 | 13 | City |
| Huntsville | 2 | 1,357 | 1,373 | -0.37% | 586 | 2 | City |
| Higbee | 3 | 440 | 448 | -0.45% | 1,111 | 0 | City |
| Clark | 4 | 236 | 242 | -0.42% | 395 | 1 | City |
| Cairo | 5 | 202 | 205 | -0.49% | 673 | 0 | Village |
| Renick | 6 | 149 | 150 | -0.67% | 413 | 0 | Village |
| Jacksonville | 7 | 122 | 123 | -0.81% | 1,109 | 0 | Village |
| Clifton Hill | 8 | 83 | 85 | -1.19% | 474 | 0 | City |
Moberly is the largest city in Randolph County, with a population of 13,731.
Clifton Hill is the smallest city in Randolph County, with a population of 83.
There are 8 cities in Randolph County, Missouri.