| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Ste. Genevieve | 1 | 5,075 | 4,998 | 0.2% | 1,302 | 4 | City |
| Bloomsdale | 2 | 693 | 641 | 1.46% | 426 | 2 | City |
| St. Mary | 3 | 312 | 309 | 0% | 521 | 1 | City |
Ste. Genevieve is the largest city in Ste. Genevieve County, with a population of 5,075.
St. Mary is the smallest city in Ste. Genevieve County, with a population of 312.
There are 3 cities in Ste. Genevieve County, Missouri.