| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Marshall | 1 | 13,752 | 13,786 | -0.1% | 1,359 | 10 | City |
| Slater | 2 | 1,819 | 1,836 | -0.27% | 1,258 | 1 | City |
| Sweet Springs | 3 | 1,323 | 1,322 | 0% | 796 | 2 | City |
| Blackburn | 4 | 224 | 226 | -0.44% | 725 | 0 | City |
| Malta Bend | 5 | 189 | 191 | -0.53% | 747 | 0 | Town |
| Gilliam | 6 | 182 | 179 | 0% | 734 | 0 | City |
| Nelson | 7 | 148 | 150 | -0.67% | 450 | 0 | City |
| Miami | 8 | 142 | 144 | -0.7% | 254 | 1 | City |
| Mount Leonard | 9 | 64 | 65 | -1.54% | 615 | 0 | Town |
| Arrow Rock | 10 | 57 | 57 | 0% | 429 | 0 | Town |
| Grand Pass | 11 | 50 | 50 | 0% | 459 | 0 | Village |
Marshall is the largest city in Saline County, with a population of 13,752.
Grand Pass is the smallest city in Saline County, with a population of 50.
There are 11 cities in Saline County, Missouri.