| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Fayette | 1 | 2,855 | 2,796 | 0.25% | 1,288 | 2 | City |
| Glasgow | 2 | 1,077 | 1,088 | -0.28% | 800 | 1 | City |
| New Franklin | 3 | 1,024 | 1,026 | -0.19% | 773 | 1 | City |
| Armstrong | 4 | 240 | 242 | -0.41% | 293 | 1 | City |
| Franklin | 5 | 66 | 67 | -1.49% | 286 | 0 | City |
Fayette is the largest city in Howard County, with a population of 2,855.
Franklin is the smallest city in Howard County, with a population of 66.
There are 5 cities in Howard County, Missouri.