| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Noel | 1 | 2,191 | 2,127 | 0.46% | 1,082 | 2 | City |
| Anderson | 2 | 2,079 | 2,039 | 0.29% | 915 | 2 | City |
| Goodman | 3 | 1,341 | 1,199 | 1.59% | 1,011 | 1 | City |
| Southwest City | 4 | 980 | 920 | 1.14% | 670 | 1 | Town |
| Pineville | 5 | 845 | 792 | 1.08% | 257 | 3 | City |
| Jane | 6 | 414 | 357 | 2.22% | 139 | 3 | Town |
| Lanagan | 7 | 380 | 374 | 0.26% | 404 | 1 | Town |
| Ginger Blue | 8 | 34 | 34 | 0% | 130 | 0 | Village |
Noel is the largest city in McDonald County, with a population of 2,191.
Ginger Blue is the smallest city in McDonald County, with a population of 34.
There are 8 cities in McDonald County, Missouri.