22 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Scioto township | 1 | 27,215 | 27,867 | -0.39% | 683 | 39.82 | Township |
| Chillicothe | 2 | 21,799 | 22,038 | -0.22% | 2,076 | 10.50 | City |
| Bainbridge township | 3 | 12,895 | 12,914 | -0.09% | 505 | 25.56 | Township |
| Union township | 4 | 12,768 | 12,587 | 0.61% | 192 | 66.39 | Township |
| Bainbridge | 5 | 10,193 | 7,951 | 4.74% | 815 | 12.50 | CDP |
| Huntington township | 6 | 6,146 | 6,128 | 0.18% | 103 | 59.57 | Township |
| Concord township | 7 | 4,659 | 4,705 | -0.11% | 62 | 75.70 | Township |
| Twin township | 8 | 3,381 | 3,399 | 0% | 56 | 60.19 | Township |
| Kingston township | 9 | 2,784 | 2,424 | 2.54% | 117 | 23.80 | Township |
| Liberty township | 10 | 2,577 | 2,593 | -0.04% | 75 | 34.31 | Township |
| Buckskin township | 11 | 2,054 | 2,037 | 0.24% | 41 | 50.29 | Township |
| Paxton township | 12 | 1,883 | 1,895 | 0% | 59 | 31.76 | Township |
| Paint township | 13 | 1,310 | 1,307 | 0.15% | 37 | 35.54 | Township |
| Kingston | 14 | 1,234 | 1,258 | -0.4% | 3,335 | 0.37 | Village |
| Frankfort | 15 | 1,099 | 1,119 | -0.36% | 2,189 | 0.50 | Village |
| Bainbridge | 16 | 747 | 761 | -0.4% | 1,468 | 0.51 | Village |
| Londonderry township | 17 | 705 | 704 | 0.28% | 19 | 36.35 | Township |
| Bourneville | 18 | 446 | 257 | 3.72% | 887 | 0.50 | CDP |
| Richmond Dale | 19 | 434 | 584 | 0.7% | 868 | 0.50 | CDP |
| Clarksburg | 20 | 399 | 408 | -0.5% | 2,509 | 0.16 | Village |
| Adelphi | 21 | 314 | 318 | -0.32% | 1,146 | 0.27 | Village |
| South Salem | 22 | 211 | 213 | 0% | 1,172 | 0.18 | Village |
Scioto township is the largest city in Ross County, with a population of 27,215.
South Salem is the smallest city in Ross County.
There are 22 cities in Ross County, Ohio.