| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Chillicothe | 1 | 21,752 | 22,041 | -0.29% | 2,072 | 11 | City |
| Kingston | 2 | 1,231 | 1,255 | -0.4% | 3,327 | 0 | Village |
| Frankfort | 3 | 1,089 | 1,116 | -0.46% | 2,169 | 1 | Village |
| Bainbridge | 4 | 731 | 762 | -0.81% | 1,436 | 1 | Village |
| Clarksburg | 5 | 398 | 407 | -0.5% | 2,503 | 0 | Village |
| Adelphi | 6 | 311 | 318 | -0.64% | 1,135 | 0 | Village |
| South Salem | 7 | 206 | 212 | -0.48% | 1,144 | 0 | Village |
Chillicothe is the largest city in Ross County, with a population of 21,752.
South Salem is the smallest city in Ross County, with a population of 206.
There are 7 cities in Ross County, Ohio.