5 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Portsmouth | 1 | 17,130 | 18,207 | -1.03% | 1,597 | 11 | City |
| New Boston | 2 | 2,191 | 2,299 | -0.81% | 1,953 | 1 | Village |
| South Webster | 3 | 642 | 668 | -0.62% | 489 | 1 | Village |
| Rarden | 4 | 140 | 146 | -0.71% | 660 | 0 | Village |
| Otway | 5 | 87 | 93 | -1.14% | 497 | 0 | Village |
Portsmouth is the largest city in Scioto County, with a population of 17,130.
Otway is the smallest city in Scioto County, with a population of 87.
There are 5 cities in Scioto County, Ohio.