14 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lawton | 1 | 89,940 | 90,374 | -0.1% | 1,104 | 81 | City |
| Elgin | 2 | 3,627 | 3,556 | 0.39% | 971 | 4 | City |
| Cache | 3 | 3,236 | 2,948 | 1.79% | 888 | 4 | City |
| Fletcher | 4 | 1,261 | 1,211 | 0.8% | 656 | 2 | Town |
| Central High | 5 | 1,244 | 1,182 | 0.97% | 24 | 53 | Town |
| Geronimo | 6 | 1,160 | 1,158 | 0% | 778 | 1 | Town |
| Bray | 7 | 1,007 | 955 | 1% | 16 | 62 | Town |
| Sterling | 8 | 667 | 672 | -0.15% | 811 | 1 | Town |
| Medicine Park | 9 | 489 | 412 | 3.16% | 221 | 2 | Town |
| Chattanooga | 10 | 409 | 404 | 0.25% | 781 | 1 | Town |
| Indiahoma | 11 | 273 | 276 | -0.36% | 982 | 0 | Town |
| Lawtonka Acres | 12 | 149 | 115 | 7.19% | 601 | 0 | CDP |
| Lakeside Village | 13 | 128 | 128 | 7.56% | 454 | 0 | CDP |
| Faxon | 14 | 112 | 112 | 0% | 436 | 0 | Town |
Lawton is the largest city in Comanche County, with a population of 89,940.
Faxon is the smallest city in Comanche County, with a population of 112.
There are 14 cities in Comanche County, Oklahoma.