12 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lawton | 1 | 89,853 | 90,374 | -0.1% | 1,100 | 82 | City |
| Elgin | 2 | 3,641 | 3,556 | 0.39% | 975 | 4 | City |
| Cache | 3 | 3,294 | 2,948 | 1.79% | 904 | 4 | City |
| Fletcher | 4 | 1,271 | 1,211 | 0.79% | 661 | 2 | Town |
| Central High | 5 | 1,257 | 1,182 | 1.05% | 24 | 53 | Town |
| Geronimo | 6 | 1,161 | 1,158 | 0.09% | 779 | 1 | Town |
| Bray | 7 | 1,018 | 955 | 1.09% | 17 | 62 | Town |
| Sterling | 8 | 666 | 672 | -0.15% | 810 | 1 | Town |
| Medicine Park | 9 | 505 | 412 | 3.27% | 228 | 2 | Town |
| Chattanooga | 10 | 410 | 404 | 0.24% | 782 | 1 | Town |
| Indiahoma | 11 | 273 | 276 | 0% | 982 | 0 | Town |
| Faxon | 12 | 112 | 112 | 0% | 436 | 0 | Town |
Lawton is the largest city in Comanche County, with a population of 89,853.
Faxon is the smallest city in Comanche County, with a population of 112.
There are 12 cities in Comanche County, Oklahoma.