14 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Lawton | 1 | 90,169 | 90,359 | -0.04% | 1,107 | 81.44 | City |
| Elgin | 2 | 3,648 | 3,557 | 0.5% | 976 | 3.74 | City |
| Cache | 3 | 3,260 | 2,947 | 1.97% | 894 | 3.65 | City |
| Fletcher | 4 | 1,266 | 1,213 | 0.88% | 658 | 1.92 | Town |
| Central High | 5 | 1,258 | 1,182 | 1.21% | 24 | 52.90 | Town |
| Geronimo | 6 | 1,167 | 1,159 | 0.17% | 783 | 1.49 | Town |
| Bray | 7 | 1,023 | 953 | 1.39% | 17 | 61.59 | Town |
| Sterling | 8 | 667 | 671 | -0.15% | 811 | 0.82 | Town |
| Medicine Park | 9 | 493 | 412 | 3.35% | 223 | 2.21 | Town |
| Chattanooga | 10 | 410 | 402 | 0.49% | 782 | 0.52 | Town |
| Indiahoma | 11 | 276 | 278 | 0% | 993 | 0.28 | Town |
| Lawtonka Acres | 12 | 149 | 115 | 7.19% | 601 | 0.25 | CDP |
| Lakeside Village | 13 | 128 | 128 | 7.56% | 454 | 0.28 | CDP |
| Faxon | 14 | 113 | 113 | 0% | 440 | 0.26 | Town |
Lawton is the largest city in Comanche County, with a population of 90,169.
Faxon is the smallest city in Comanche County.
There are 14 cities in Comanche County, Oklahoma.