8 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Altus | 1 | 18,590 | 18,702 | -0.12% | 1,020 | 18.22 | City |
| Blair | 2 | 708 | 718 | -0.28% | 1,484 | 0.48 | Town |
| Olustee | 3 | 462 | 466 | -0.22% | 555 | 0.83 | Town |
| Eldorado | 4 | 312 | 317 | -0.32% | 425 | 0.73 | Town |
| Martha | 5 | 157 | 161 | -0.63% | 623 | 0.25 | Town |
| Headrick | 6 | 77 | 76 | 0% | 348 | 0.22 | Town |
| Elmer | 7 | 62 | 64 | 0% | 147 | 0.42 | Town |
| Friendship | 8 | 23 | 23 | 0% | 153 | 0.15 | Town |
Altus is the largest city in Jackson County, with a population of 18,590.
Friendship is the smallest city in Jackson County.
There are 8 cities in Jackson County, Oklahoma.