28 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bloomsburg | 1 | 13,578 | 12,702 | 1.09% | 3,123 | 4 | Town |
| Berwick | 2 | 10,331 | 10,333 | 0% | 3,361 | 3 | Borough |
| Scott | 3 | 5,664 | 5,507 | 0.09% | 814 | 7 | Township |
| Briar Creek | 4 | 3,035 | 2,987 | 0.23% | 145 | 21 | Township |
| Berwick | 5 | 2,504 | 2,399 | 0.72% | 325 | 8 | Township |
| Hemlock | 6 | 2,389 | 2,213 | 2.01% | 136 | 18 | Township |
| North Centre | 7 | 2,122 | 2,036 | 0.38% | 142 | 15 | Township |
| South Centre | 8 | 1,937 | 1,903 | 0.31% | 357 | 5 | Township |
| Greenwood | 9 | 1,928 | 1,882 | 0.63% | 68 | 28 | Township |
| Benton | 10 | 1,770 | 1,718 | 0.8% | 74 | 24 | Township |
| Fishing Creek | 11 | 1,599 | 1,522 | 0.95% | 56 | 28 | Township |
| Catawissa | 12 | 1,536 | 1,538 | 0% | 2,994 | 1 | Borough |
| Locust | 13 | 1,482 | 1,453 | 0.41% | 83 | 18 | Township |
| Benton | 14 | 1,380 | 1,316 | 0.8% | 70 | 20 | Township |
| Main | 15 | 1,292 | 1,267 | 0.31% | 80 | 16 | Township |
| Montour | 16 | 1,267 | 1,256 | 0.16% | 138 | 9 | Township |
| Orange | 17 | 1,181 | 1,161 | 0.17% | 92 | 13 | Township |
| Cleveland | 18 | 1,165 | 1,129 | 0.69% | 50 | 23 | Township |
| Pine | 19 | 1,043 | 1,012 | 0.97% | 39 | 26 | Township |
| Millville | 20 | 987 | 974 | 0.2% | 1,006 | 1 | Borough |
| Catawissa | 21 | 913 | 902 | 0.11% | 74 | 12 | Township |
| Benton | 22 | 825 | 821 | 0.12% | 1,382 | 1 | Borough |
| Briar Creek | 23 | 603 | 597 | 0.17% | 365 | 2 | Borough |
| Roaring Creek | 24 | 562 | 554 | 0.18% | 24 | 23 | Township |
| Orangeville | 25 | 476 | 476 | 0% | 1,070 | 0 | Borough |
| New Columbus | 26 | 226 | 219 | 0.44% | 73 | 3 | Borough |
| Stillwater | 27 | 199 | 199 | 0% | 64 | 3 | Borough |
| Centralia | 28 | 4 | 4 | 0% | 17 | 0 | Borough |
Bloomsburg is the largest city in Columbia County, with a population of 13,578.
Centralia is the smallest city in Columbia County, with a population of 4.
There are 28 cities in Columbia County, Pennsylvania.