56 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| White | 1 | 14,819 | 15,333 | -1.13% | 350 | 42 | Township |
| North Union | 2 | 11,355 | 11,824 | -0.65% | 293 | 39 | Township |
| South Union | 3 | 10,328 | 10,871 | -0.88% | 616 | 17 | Township |
| Uniontown | 4 | 9,450 | 9,969 | -1.09% | 4,610 | 2 | City |
| Smithfield | 5 | 7,853 | 7,970 | -0.19% | 342 | 23 | Township |
| Connellsville | 6 | 6,597 | 7,022 | -1.27% | 3,023 | 2 | City |
| Bullskin | 7 | 6,442 | 6,735 | -0.72% | 146 | 44 | Township |
| Dunbar | 8 | 6,374 | 6,653 | -0.69% | 108 | 59 | Township |
| Georges | 9 | 6,054 | 6,341 | -0.75% | 127 | 48 | Township |
| Redstone | 10 | 4,863 | 5,064 | -0.63% | 213 | 23 | Township |
| German | 11 | 4,452 | 4,665 | -0.78% | 133 | 33 | Township |
| Smithfield | 12 | 4,284 | 4,622 | -0.83% | 779 | 6 | Township |
| Menallen | 13 | 3,994 | 4,085 | -0.52% | 187 | 21 | Township |
| Wharton | 14 | 3,328 | 3,352 | -0.3% | 36 | 92 | Township |
| Masontown | 15 | 3,125 | 3,265 | -0.89% | 2,090 | 1 | Borough |
| Saltlick | 16 | 2,913 | 3,037 | -0.65% | 78 | 38 | Township |
| Springhill | 17 | 2,605 | 2,723 | -0.72% | 77 | 34 | Township |
| Perry | 18 | 2,241 | 2,338 | -0.71% | 110 | 20 | Township |
| Oliver | 19 | 2,104 | 2,044 | 0.86% | 256 | 8 | Township |
| Brownsville | 20 | 2,079 | 2,176 | -0.95% | 2,128 | 1 | Borough |
| Oliver | 21 | 2,034 | 2,062 | -0.29% | 58 | 35 | Township |
| Connellsville | 22 | 1,988 | 2,072 | -0.7% | 175 | 11 | Township |
| South Connellsville | 23 | 1,825 | 1,913 | -0.98% | 1,086 | 2 | Borough |
| North Belle Vernon | 24 | 1,818 | 1,872 | -0.6% | 4,329 | 0 | Borough |
| Fairchance | 25 | 1,800 | 1,877 | -0.88% | 1,516 | 1 | Borough |
| Farmington | 26 | 1,731 | 1,776 | -0.4% | 28 | 62 | Township |
| Upper Tyrone | 27 | 1,687 | 1,763 | -0.71% | 216 | 8 | Township |
| Henry Clay | 28 | 1,680 | 1,763 | -0.71% | 33 | 51 | Township |
| Perryopolis | 29 | 1,600 | 1,702 | -1.3% | 1,092 | 1 | Borough |
| Smithfield | 30 | 1,456 | 1,452 | -0.14% | 35 | 42 | Township |
| White | 31 | 1,280 | 1,315 | -0.23% | 1,847 | 1 | Township |
| Farmington | 32 | 1,258 | 1,281 | -0.24% | 37 | 34 | Township |
| Point Marion | 33 | 1,101 | 1,153 | -0.99% | 2,719 | 0 | Borough |
| Speers | 34 | 1,056 | 1,080 | -0.47% | 1,110 | 1 | Borough |
| Lower Tyrone | 35 | 1,026 | 1,068 | -0.68% | 65 | 16 | Township |
| Belle Vernon | 36 | 979 | 1,024 | -0.91% | 3,751 | 0 | Borough |
| Oliver | 37 | 976 | 1,006 | -0.51% | 33 | 30 | Township |
| Dunbar | 38 | 968 | 1,013 | -0.92% | 1,675 | 1 | Borough |
| West Brownsville | 39 | 964 | 976 | -0.31% | 742 | 1 | Borough |
| White | 40 | 905 | 915 | 0.11% | 45 | 20 | Township |
| New Salem | 41 | 834 | 821 | 0.24% | 1,763 | 0 | Borough |
| Smithfield | 42 | 790 | 830 | -1% | 1,103 | 1 | Borough |
| Everson | 43 | 735 | 767 | -0.94% | 3,403 | 0 | Borough |
| Farmington | 44 | 661 | 663 | -0.15% | 21 | 32 | Township |
| Stewart | 45 | 620 | 619 | 0.98% | 12 | 50 | Township |
| Brownsville | 46 | 512 | 534 | -0.58% | 340 | 2 | Township |
| Newell | 47 | 490 | 513 | -1.01% | 833 | 1 | Borough |
| Fayette City | 48 | 480 | 504 | -1.03% | 2,162 | 0 | Borough |
| Vanderbilt | 49 | 393 | 411 | -1.01% | 2,124 | 0 | Borough |
| Dawson | 50 | 334 | 351 | -1.18% | 1,931 | 0 | Borough |
| Markleysburg | 51 | 236 | 243 | -0.84% | 795 | 0 | Borough |
| Allison | 52 | 229 | 229 | 0% | 150 | 2 | Township |
| New Centerville | 53 | 122 | 127 | -0.81% | 859 | 0 | Borough |
| Casselman | 54 | 121 | 101 | 3.42% | 602 | 0 | Borough |
| Ohiopyle | 55 | 35 | 38 | -2.78% | 84 | 0 | Borough |
| Seven Springs | 56 | 24 | 24 | 0% | 22 | 1 | Borough |
White is the largest city in Fayette County, with a population of 14,819.
Seven Springs is the smallest city in Fayette County, with a population of 24.
There are 56 cities in Fayette County, Pennsylvania.