4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Hilton Head Island | 1 | 38,301 | 37,586 | 0.37% | 926 | 41 | Town |
| Bluffton | 2 | 38,101 | 28,324 | 5.41% | 731 | 52 | Town |
| Port Royal | 3 | 16,988 | 14,581 | 2.91% | 880 | 19 | Town |
| Beaufort | 4 | 14,511 | 13,625 | 1.23% | 594 | 24 | City |
Hilton Head Island is the largest city in Beaufort County, with a population of 38,301.
Beaufort is the smallest city in Beaufort County, with a population of 14,511.
There are 4 cities in Beaufort County, South Carolina.