8 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Cheraw | 1 | 4,919 | 5,000 | -0.26% | 826 | 6 | Town |
| Pageland | 2 | 2,548 | 2,470 | 0.51% | 525 | 5 | Town |
| Chesterfield | 3 | 1,359 | 1,335 | 0.3% | 333 | 4 | Town |
| McBee | 4 | 825 | 786 | 0.86% | 628 | 1 | Town |
| Jefferson | 5 | 796 | 772 | 0.51% | 442 | 2 | Town |
| Ruby | 6 | 326 | 313 | 0.62% | 132 | 2 | Town |
| Patrick | 7 | 290 | 278 | 0.69% | 302 | 1 | Town |
| Mount Croghan | 8 | 135 | 135 | 0% | 178 | 1 | Town |
Cheraw is the largest city in Chesterfield County, with a population of 4,919.
Mount Croghan is the smallest city in Chesterfield County, with a population of 135.
There are 8 cities in Chesterfield County, South Carolina.