4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Manning | 1 | 3,813 | 3,905 | -0.5% | 1,299 | 3 | City |
| Summerton | 2 | 774 | 809 | -0.9% | 572 | 1 | Town |
| Turbeville | 3 | 738 | 760 | -0.67% | 551 | 1 | Town |
| Paxville | 4 | 224 | 227 | -0.44% | 213 | 1 | Town |
Manning is the largest city in Clarendon County, with a population of 3,813.
Paxville is the smallest city in Clarendon County, with a population of 224.
There are 4 cities in Clarendon County, South Carolina.