3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Waynesboro | 1 | 2,321 | 2,315 | 0.04% | 542 | 4.28 | City |
| Clifton | 2 | 1,991 | 2,656 | -6.26% | 358 | 5.56 | City |
| Collinwood | 3 | 912 | 896 | 0.33% | 328 | 2.78 | City |
Waynesboro is the largest city in Wayne County, with a population of 2,321.
Collinwood is the smallest city in Wayne County.
There are 3 cities in Wayne County, Tennessee.