| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Waynesboro | 1 | 2,321 | 2,312 | 0.09% | 542 | 4 | City |
| Clifton | 2 | 2,208 | 2,655 | -5.8% | 397 | 6 | City |
| Collinwood | 3 | 922 | 895 | 0.33% | 332 | 3 | City |
Waynesboro is the largest city in Wayne County, with a population of 2,321.
Collinwood is the smallest city in Wayne County, with a population of 922.
There are 3 cities in Wayne County, Tennessee.