| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Greeneville | 1 | 16,258 | 15,515 | 0.72% | 957 | 17 | Town |
| Tusculum | 2 | 3,446 | 3,294 | 0.73% | 709 | 5 | City |
| Mosheim | 3 | 2,563 | 2,479 | 0.63% | 401 | 6 | Town |
| Baileyton | 4 | 469 | 436 | 1.08% | 289 | 2 | Town |
Greeneville is the largest city in Greene County, with a population of 16,258.
Baileyton is the smallest city in Greene County, with a population of 469.
There are 4 cities in Greene County, Tennessee.