21 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Spokane | 1 | 229,608 | 229,205 | 0.04% | 3,339 | 68.76 | City |
| Spokane Valley | 2 | 111,371 | 103,531 | 1.43% | 2,953 | 37.72 | City |
| Liberty Lake | 3 | 13,888 | 12,137 | 2.59% | 2,189 | 6.34 | City |
| Cheney | 4 | 12,117 | 13,374 | -2.03% | 2,791 | 4.34 | City |
| Airway Heights | 5 | 11,093 | 10,793 | 0.54% | 1,846 | 6.01 | City |
| Fairwood | 6 | 10,809 | 9,790 | 1.83% | 2,706 | 3.99 | CDP |
| Mead | 7 | 7,146 | 6,995 | -0.13% | 984 | 7.26 | CDP |
| Country Homes | 8 | 6,350 | 5,877 | 0.54% | 3,802 | 1.67 | CDP |
| Otis Orchards-East Farms | 9 | 5,569 | 5,968 | -0.77% | 693 | 8.03 | CDP |
| Town Country | 10 | 5,340 | 5,402 | 0.62% | 4,450 | 1.20 | CDP |
| Deer Park | 11 | 5,226 | 4,405 | 3.24% | 759 | 6.89 | City |
| Medical Lake | 12 | 5,009 | 4,878 | 0.52% | 1,486 | 3.37 | City |
| Fairchild AFB | 13 | 3,286 | 3,464 | 1.05% | 496 | 6.62 | CDP |
| Millwood | 14 | 1,838 | 1,882 | -0.49% | 2,641 | 0.70 | City |
| Rockford | 15 | 605 | 527 | 2.72% | 911 | 0.66 | Town |
| Fairfield | 16 | 588 | 593 | -0.17% | 955 | 0.62 | Town |
| Four Lakes | 17 | 577 | 515 | 0.7% | 187 | 3.09 | CDP |
| Spangle | 18 | 275 | 282 | -0.36% | 788 | 0.35 | City |
| Latah | 19 | 171 | 178 | -0.58% | 534 | 0.32 | Town |
| Waverly | 20 | 119 | 121 | 0% | 288 | 0.41 | Town |
| Green Bluff | 21 | 84 | 366 | -34.88% | 12 | 7.07 | CDP |
Spokane is the largest city in Spokane County, with a population of 229,608.
Green Bluff is the smallest city in Spokane County.
There are 21 cities in Spokane County, Washington.