4 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Madison | 1 | 2,674 | 2,897 | -1.66% | 350 | 8 | City |
| Danville | 2 | 627 | 671 | -1.42% | 645 | 1 | Town |
| Whitesville | 3 | 335 | 368 | -2.05% | 1,496 | 0 | Town |
| Sylvester | 4 | 148 | 163 | -1.99% | 2,902 | 0 | Town |
Madison is the largest city in Boone County, with a population of 2,674.
Sylvester is the smallest city in Boone County, with a population of 148.
There are 4 cities in Boone County, West Virginia.