| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Madison | 1 | 2,631 | 2,894 | -1.76% | 345 | 8 | City |
| Danville | 2 | 620 | 675 | -1.59% | 638 | 1 | Town |
| Whitesville | 3 | 333 | 369 | -2.06% | 1,487 | 0 | Town |
| Sylvester | 4 | 145 | 163 | -2.68% | 2,843 | 0 | Town |
Madison is the largest city in Boone County, with a population of 2,631.
Sylvester is the smallest city in Boone County, with a population of 145.
There are 4 cities in Boone County, West Virginia.