| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Wheeling | 1 | 25,447 | 26,934 | -0.91% | 1,871 | 14 | City |
| West Liberty | 2 | 1,425 | 1,449 | -0.28% | 1,305 | 1 | Town |
| Triadelphia | 3 | 644 | 684 | -1.08% | 957 | 1 | Town |
| Valley Grove | 4 | 266 | 283 | -1.12% | 486 | 1 | Village |
Wheeling is the largest city in Ohio County, with a population of 25,447.
Valley Grove is the smallest city in Ohio County, with a population of 266.
There are 4 cities in Ohio County, West Virginia.