Santa Fe's 2021 population is now estimated at 569,991. In 1950, the population of Santa Fe was 214,298. Santa Fe has grown by 7,074 since 2015, which represents a 1.26% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Santa Fe, which typically includes Santa Fe's population in addition to adjacent suburban areas.