Santo Domingo's 2021 population is now estimated at 3,388,809. In 1950, the population of Santo Domingo was 180,283. Santo Domingo has grown by 71,025 since 2015, which represents a 2.14% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects. These estimates represent the Urban agglomeration of Santo Domingo, which typically includes Santo Domingo's population in addition to adjacent suburban areas.