Deir ez-Zor's 2025 population is now estimated at 378,586. In 1950, the population of Deir ez-Zor was 26,387. Deir ez-Zor has grown by 15,496 in the last year, which represents a 4.27% annual change. These population estimates and projections come from the latest revision of the UN World Urbanization Prospects . These estimates represent the Urban agglomeration of Deir ez-Zor, which typically includes Deir ez-Zor's population in addition to adjacent suburban areas.
| City | 2025 Pop. ↓ | Growth |
|---|---|---|
| Damascus | 2,799,960 | |
| Aleppo | 2,438,480 | |
| Homs | 1,563,600 | |
| Hamah | 1,078,650 | |
| Latakia | 340,181 | |
| Ar Raqqah | 177,636 | |
| Al Bab | 130,745 | |
| Idlib | 128,840 | |
| Douma | 111,864 | |
| Manbij | 99,497 | |
| Dar'a | 97,969 | |
| As Salamiyah | 94,887 | |
| Tartouss | 89,457 | |
| Ath Thawrah | 87,880 | |
| Al Hasakah | 81,539 | |
| Darayya | 71,596 | |
| I`zaz | 66,138 | |
| Jablah | 65,915 | |
| As Safirah | 63,708 | |
| As Suwayda' | 59,052 | |
| Albu Kamal | 57,572 | |
| At Tall | 55,561 | |
| Al Mayadin | 54,534 | |
| Ar Rastan | 53,152 | |
| Tadmur | 51,015 | |
| 'Ayn al 'Arab | 50,000 | |
| An Nabk | 49,372 | |
| Khan Shaykhun | 48,975 | |
| `Afrin | 48,693 | |
| Kafranbel | 45,652 | |
| `Irbin | 42,474 | |
| Al Qusayr | 41,062 | |
| Yabrud | 40,502 | |
| Jisr ash Shughur | 39,311 | |
| Baniyas | 39,066 | |
| Tallbisah | 38,491 | |
| Harasta | 37,348 | |
| Al Qunaytirah | 36,143 | |
| Tadif | 34,670 | |
| Saraqib | 34,231 | |
| Jayrud | 32,352 | |
| Masyaf | 32,262 | |
| Ma`arratmisrin | 32,163 | |
| Al Qaryatayn | 31,748 | |
| Salqin | 31,608 | |
| Tafas | 31,249 | |
| Souran | 30,716 | |
| Binnish | 30,354 | |
| Jasim | 30,283 | |
| Tallkalakh | 29,754 | |
| Az Zabadani | 29,549 | |
| Tayyibat al Imam | 29,259 | |
| Hajin | 29,237 | |
| Inkhil | 29,076 | |
| Dayr Hafir | 28,905 | |
| Satita | 27,815 | |
| Ash Shaykh Miskin | 25,920 | |
| As Sanamayn | 25,702 | |
| Tall Rif`at | 25,658 | |
| Nubl | 25,546 | |
| Subaykhan | 25,514 | |
| Jarabulus | 24,997 | |
| Al Harak | 23,784 | |
| Al Kiswah | 23,526 | |
| Halfaya | 23,403 | |
| Kafr Takharim | 22,436 | |
| Ad Dana | 21,987 | |
| Kafr Zayta | 21,845 | |
| Kafr Laha | 21,819 | |
| Ad Darbasiyah | 21,481 | |
| Qarah | 20,656 | |
| Qatana | 18,511 | |
| Al Qutayfah | 16,118 | |
| Shahba | 14,784 | |
| Murak | 14,307 | |
| Izra` | 13,882 | |
| Salakhid | 12,842 | |
| Ad Duraykish | 11,918 |
