Clio
- County:
- Barbour County
- County Seat:
- No
- Area (mi²):
- 10.066
- State:
- Alabama
Clio is a city located in Barbour County, Alabama. Clio has a 2026 population of 1,190. Clio is currently declining at a rate of -1.08% annually and its population has decreased by -2.22% since the most recent census, which recorded a population of 1,217 in 2020.